Skincare science: Update on topical retinoids

Skincare science: update on topical retinoids.

According to the author, the single most effective component in a skincare regimen for reversal of photoaging is the use of retinoids. Here is a guide to the mechanism and application of various formulations of retinoids, and a comprehensive skin regimen incorporating tretinoin.

Understanding Topical Retinoids

Retinoids have been a mainstay treatment in dermatology for over fifty years . They are synthetic compounds derived from vitamin A. Studies have shown that these derivatives help clear comedonaland inflammatory lesions while controlling the bacteria implicated in most types of acne. Originally marketed as Retin A, these topical retinoids have gone through numerous transformations over the years...

Tolerability of Topical Retinoids

Cosmeceuticals: focus on topical retinoids in photoaging.

Evidence from a randomized clinical trial showed that, in spite of the many surgical procedures effective in ameliorating the clinical appearance of photoaged skin, the only medical therapy with proven benefits in photoaged skin are topical retinoids, in particular tretinoin, isotretinoin, and tazarotene. The application of retinoids might not only clinically and biochemically repair photoaged ...

Topical Update

Human papillomavirus (HPV) infection is of much current interest, with the availability and increasing use of the vaccines in different localities including Hong Kong. In this issue of the Topical Update, Prof. Paul Chan shares the local epidemiology of cervical HPV infection, in aid of formulating strategies to maximize the clinical benefits and cost-effectiveness of HPV-based diagnostic tests...